Goal understands that Reds boss Jurgen Klopp has taken the bold call to rest Mignolet, who has started his side’s first four games in all competitions.
Liverpool 8/1 with dabblebet to win 2-1
The decision has paved the way for Karius, who struggled last season following his move from Mainz, to seize a big opportunity in Liverpool’s goalkeeping department.
Karius, 24, featured as Liverpool’s regular goalkeeper at the start of the 2016/17 campaign but was later dropped for Mignolet after a series of errors between the sticks.
Mignolet then went on to help the Merseysiders pip Arsenal to fourth place towards the end of the season, playing a key role in their crucial 2-1 victory over Stoke City in April.
However, Karius is expected to earn a recall as Arsenal travel to Anfield hoping to bounce back from their 1-0 defeat against Stoke City last time out.
The Gunners, who opened up the new season with a 4-3 victory over Leicester City, will have Alexis Sanchez available for the game after Arsene Wenger confirmed he is ready to face Liverpool.
Wenger’s men come up against a Liverpool side who are in high spirits after securing their place in the Champions League group stage in midweek, downing Hoffenheim 6-3 on aggregate.
